Vol. 32 (2022)
Artículos de Investigación

Evaluation of lymphocyte subpopulations in seropositive individuals to Helicobacter pylori

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  • Monika Palacios Martínez,
  • Oralia Nájera Medina,
  • Marco Gonázlez López,
  • Karina Ramírez Navarro,
  • Patricia Concepción Solís Chávez,
  • Elena Marcia Gutiérrez Cárdenas
Monika Palacios Martínez
DEPARTAMENTO PRODUCCIÓN AAGRÍCOLA Y ANIMAL, UNIVERSDIDAD AUTÓNOMA METROPOLITANA- UNIDAD XOCHIMILCO
DOI: https://doi.org/10.15174/au.2022.3221

Published 2022-02-02

How to Cite

Palacios Martínez, M., Nájera Medina, O. ., Gonázlez López, M., Ramírez Navarro, K., Solís Chávez, P. C., & Gutiérrez Cárdenas, E. M. (2022). Evaluation of lymphocyte subpopulations in seropositive individuals to Helicobacter pylori. Acta Universitaria, 32. https://doi.org/10.15174/au.2022.3221

Abstract

Helicobacter pylori (H. pylori) infections are considered a public health problem due to its high morbidity rate in the
Mexican population. Therefore, this work is focused on the detection of anti-IgA-H. pylori by ELISA blood test and
the evaluation of lymphocyte subpopulations by flow cytometry in peripheral blood of adult population from a rural area of the state of Morelos. We worked with 79 adult participants (aged 42 ± 13.7 years), of which 57% (n = 45) were
seropositive and 43% (n = 24) seronegative. No statistically significant differences were found in leukocytes, or effector
cells, only a small tendency to increase both CD4+ and CD8+ memory cells, in H. pylori seropositive individuals, and
a decrease in double positive CD8+ cells (CD8+CD45RA+CD45RO+, p < 0.05). There are probably no relevant differences due to the capacity of the bacterium to evade the immune response.

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